Pertussis is a highly contagious acute respiratory infectious disease caused by Bordetella pertussis. Pertussis transmits predominantly through droplets and poses a significant threat to life, especially in severe cases. In recent years, pertussis resurgence has occurred globally with evolving epidemiological patterns. The prevalence of pertussis in China is also increasing. A variety of factors influence pertussis resurgence. This paper aims to systematically sort out and analyze the causes of pertussis resurgence in China, and put forward some prevention and control suggestions, providing references for preventing this type of infectious disease.