百日咳是高传染性的呼吸道疾病，随着近年来病例的增加，百日咳受到广泛关注。接种疫苗是目前预防百日咳最有效的手段，加强新型疫苗的研发是百日咳防治的重点工作之一。此文综述了百日咳的流行趋势、再现原因以及最新百日咳疫苗研发进展，为新型百日咳疫苗的研发提供参考。

Pertussis is a highly contagious respiratory disease. With the increase in pertussis cases in recent years, it has become more and more concerned. Currently, vaccination is the most effective prevention method for pertussis, and developing new vaccines is a major priority in pertussis prevention and treatment. This paper summarizes the current pertussis epidemiological trends, analyzes the causes of pertussis resurgence, and tracks the latest progress in pertussis vaccine development, in order to provide a reference for developing novel pertussis vaccines.