低白蛋白血症是腹部胃肠大手术预后不良的独立预测因子。为避免腹部术后低蛋白血症的发生，人血清白蛋白在腹部术后并低白蛋白血症患者中的应用比较普遍。但是，腹部术后应用人血清白蛋白是否具有临床获益，目前尚存在争议。此文综述当前白蛋白在腹部围术期中的作用、病理生理变化、临床治疗获益以及营养价值等，旨在加强临床医师对白蛋白的正确认识及合理应用，以利于患者的术后管理，降低用药费用。

Hypoalbuminemia is an independent predictor of poor prognosis in major abdominal gastrointestinal surgery. To avoid the occurrence of hypoalbuminemia after abdominal surgery, the application of human serum albumin is relatively common in patients with hypoalbuminemia after abdominal surgery due to insufficient level of albumin. However, there is still controversy regarding the clinical benefits of using human serum albumin after abdominal surgery.This article reviews the current role, pathological and physiological changes, clinical treatment benefits, and nutritional value of albumin in the perioperative period of abdominal surgery, in order to strengthen clinical physicians' correct understanding and rational application of human albumin, in turn to facilitate postoperative management of patients and reduce medication costs.