综述

柯萨奇病毒A组6型研究进展

  • 董方玉 苏瑶 马超 吴星 梁争论
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  • 100000 北京,中国食品药品检定研究院肝炎疫苗室(董方玉、苏瑶、吴星、梁争论);730046 兰州生物制品研究所有限责任公司第二研究室(董方玉、马超)

网络出版日期: 2025-08-16

基金资助

国家科技重大专项(2016ZX09101120)

Progress in research on coxsackievirus A6

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  • *Division of Hepatitis Virus Vaccine, National Institutes for Food and Drug Control, Beijing 100000, China; #Division of Enterovirus Virus Vaccines, Lanzhou Institute of Biological Products, Co., Ltd., Lanzhou 730046, China;

Online published: 2025-08-16

Supported by

National Science and Technology Major Project of China(2016ZX09101120)

摘要

 柯萨奇病毒A组6型(coxsackievirus A6,CA6)是引起非典型手足口病、疱疹性咽峡炎的主要病原体,重症可出现神经及心、肺系统症状等。自2012年后,CA6因在我国多个省市呈现替代肠道病毒71型或CA16成为引起手足口病主要病原体的趋势,而引起关注。此文就CA6的流行病学、实验室诊断、动物模型及疫苗研发进展进行综述。

本文引用格式

董方玉 苏瑶 马超 吴星 梁争论 . 柯萨奇病毒A组6型研究进展[J]. 国际生物制品学杂志, 2018 , 41(3) : 136 -139,143 . DOI: 10.3760/cma.j.issn.1673-4211.2018.03.008

Abstract

Coxsackievirus A6 (CA6) is main pathogen of atypical hand, foot and mouth disease (HFMD) and herpangina,neurological disease or cardiopulmonary system disorders may be occur in severe cases. Since 2012, CA6 has drawn attention for becoming the major pathogen causing HFMD instead of enterovirus 71 and CA16 in many provinces of China. This paper summarizes research development in the epidemiological, laboratory diagnosis, animal model and vaccine development of CA6.
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