接种重组乙型肝炎疫苗低无应答的研究进展

陈小英 许国章

doi:10.3760/cma.j.issn.1673-4211.2010.04.006

国际生物制品学杂志 >

2010 , Vol. 33 >Issue 4: 190 - 194

DOI: https://doi.org/10.3760/cma.j.issn.1673-4211.2010.04.006

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接种重组乙型肝炎疫苗低无应答的研究进展

陈小英许国章

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315010 宁波市疾病预防控制中心免疫预防所（陈小英现为宁波大学在读硕士研究生）

网络出版日期: 2025-08-16

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Advances in the research of low- and non-responsiveness after immunization with recombinant hepatitis B vaccine

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Department of Immunity Prevention, Ningbo municipal Center for Disease Control and Prevention, Ningbo 315010, China

Online published: 2025-08-16

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摘要

接种乙型肝炎(乙肝)疫苗( hepatitis B vaccine) 是人群预防乙肝的关键措施, 但接种乙肝疫苗后，约5％~10％免疫人群呈现抗体低无应答。此文对接种重组乙肝疫苗低无应答的研究进展作一综述。

关键词： 肝炎疫苗,乙型;接种;低无应答

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陈小英许国章 . 接种重组乙型肝炎疫苗低无应答的研究进展[J]. 国际生物制品学杂志, 2010 , 33(4) : 190 -194 . DOI: 10.3760/cma.j.issn.1673-4211.2010.04.006

Abstract

The key strategy to prevent hepatitis B is immunization with hepatitis B vaccine, but after immunization, about 5 %-10% of the vaccinees are low- and non-responders
to hepatitis B vaccine.This review summarizes the research progress in low- and non-responsive-ness after recombinant hepatitis B vaccination.

Key words： Hepatitis B vaccine;Vaccination;Low- and non-responsiveness

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