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黏膜免疫和黏膜疫苗研究进展

  • 周祖木 史久华
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  • 325000  浙江省温州市疾病预防控制中心急性传染病防制科(周祖木); 200052  上海生物制品研究所有限责任公司第六研究室 (史久华)

网络出版日期: 2025-08-16

Advances in research of mucosal immunity and mucosal vaccines

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  • *Department of Infectious Diseases Control and Prevention, Wenzhou Center for Diseases Control and Prevention, Wenzhou 325000, China

Online published: 2025-08-16

摘要

黏膜免疫包括各种对不同病原体易感的黏膜表面。此文根据黏膜表面的多样性及其独特的组织环境探索黏膜免疫的基本原理,并基于大动物对感染和疫苗接种的免疫应答的实验研究,为研制诱导黏膜免疫的疫苗提供一些思路。

本文引用格式

周祖木 史久华 . 黏膜免疫和黏膜疫苗研究进展[J]. 国际生物制品学杂志, 2012 , 35(4) : 182 -185 . DOI: 10.3760/cma.j.issn.1673-4211.2012.04.004

Abstract

Mucosal immunity covers a variety of mucosal surfaces susceptible to different pathogens. This review explores the basic principles of mucosal immunity in light of the diversity of  mucosal surfaces  and  their  unique  tissue  environments, and offers some thoughts on approaches for developing vaccines to induce mucosal immunity, predominantly based on experiments studying immune responses to infection and vaccination in large animals.
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