EV71疫苗研制新进展

赵蕾 陈敬贤 王明丽

doi:10.3760/cma.j.issn.1673-4211.2013.02.005

国际生物制品学杂志 >

2013 , Vol. 36 >Issue 2: 74 - 77

DOI: https://doi.org/10.3760/cma.j.issn.1673-4211.2013.02.005

综述

EV71疫苗研制新进展

赵蕾陈敬贤王明丽

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230032合肥，安徽医科大学微生物学教研室（赵蕾、陈敬贤、王明丽）；10032 纽约，哥伦比亚大学病理与细胞生物学教研室（陈敬贤）

网络出版日期: 2025-08-16

基金资助

国家自然科学基金(30872253)；安徽省科技攻关计划（8010302179）

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Progress in research of enterovirus 71 vaccines

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*Department of Microbiology, Anhui Medical University, Hefei 230032, China

Online published: 2025-08-16

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摘要

肠道病毒71型（enterovirus 71，EV71）是引起手足口病和神经系统并发症的重要病原体。近几年，世界多个地区发生了由EV71感染引起的手足口病。由于目前尚无有效的抗病毒药物对患者进行治疗，因而疫苗的研制成为预防和控制EV71传播的关键。此文主要就近年EV71疫苗的研制进展做一综述。

关键词： 肠道病毒属;疫苗;手足口病

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赵蕾陈敬贤王明丽 . EV71疫苗研制新进展[J]. 国际生物制品学杂志, 2013 , 36(2) : 74 -77 . DOI: 10.3760/cma.j.issn.1673-4211.2013.02.005

Abstract

Enterovirus 71 (EV71) is known to be a causative agent of hand, foot and mouth disease (HFMD) and severe neurological complications. Many outbreaks caused by EV71 have occurred in different regions of the world. Due to lacking an effective antiviral agent, development of effective vaccines has become the top priority in terms of control strategies. This article reviews the recent advancement in the design of various kinds of vaccines against EV71.

Key words： Enterovirus;Vaccines;Hand,foot and mouth disease

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