乙型脑炎减毒活疫苗（乙脑活疫苗）是中国自主研发的疫苗，也是中国第一个通过世界卫生组织预认证的疫苗。此文介绍了乙脑活疫苗在国外进行的临床研究，包括该疫苗在亚洲不同地区人群中的免疫原性、免疫效力和安全性研究，从而为该疫苗在中国以外的乙型脑炎流行区的推广和使用提供科学依据。

 Japanese encephalitis (JE) live attenuated vaccine is an independently developed by and the first WHO prequalified vaccine product made in China. This review summarizes clinical studies of JE vaccine conducted overseas, including immunogenicity, efficacy and safety studies among populations in different Asian regions. These studies provide evidences for further ipromoting and using JE vaccine in epidemic regions outside of China.