肠道微生物群与精神疾病的关系

蔡林彬  付轶群  李明阳  林慧  周润华

doi:10.3760/cma.j.issn.1673-4211.2014.05.007

国际生物制品学杂志 >

2014 , Vol. 37 >Issue 5: 232 - 237

DOI: https://doi.org/10.3760/cma.j.issn.1673-4211.2014.05.007

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肠道微生物群与精神疾病的关系

蔡林彬付轶群李明阳林慧周润华

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200025 上海交通大学医学院免疫学与微生物学教研室

网络出版日期: 2025-08-16

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The relationship between microbiota and mental disorder

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Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Online published: 2025-08-16

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摘要

肠道微生物群种类繁多，对人类健康起至关重要作用。肠道微生物群可以影响人类的神经系统、内分泌系统、免疫系统。目前发现精神疾病中的抑郁症、焦虑症、孤独症均与肠道微生物群存在相关性，这将有望为治疗相关精神疾病提供新方法。此文就肠道微生物群与这3类精神疾病相关机制的研究做一综述。

关键词： 肠道微生物群;抑郁症;焦虑;孤独障碍

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蔡林彬付轶群李明阳林慧周润华 . 肠道微生物群与精神疾病的关系[J]. 国际生物制品学杂志, 2014 , 37(5) : 232 -237 . DOI: 10.3760/cma.j.issn.1673-4211.2014.05.007

Abstract

Microbiota, composed of deverse microorganism, plays an important role in human health, particularly in the nervous system, endocrine system and immune system. It is found that microbiota is related to several mental disorders. This finding will provide a new way for the treatment of mental disorders. This article reviews studies on the relationship between microbiota and several mental disorders including depressive disorder, anxiety disorder and autism.

Key words： Microbiota ; Depressive disorder ; Anxiety; Autistic disorder

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