蛋白质纳米颗粒作为抗原展示载体，与天然病原体大小相似，能够有效帮助抗原提高其稳定性和免疫原性。临床试验研究表明，蛋白质纳米颗粒可被应用于新型疫苗的开发。此文对蛋白质纳米颗粒疫苗的免疫学特性，以及蛋白质颗粒在疫苗研发中的应用进行综述，旨在为蛋白质纳米颗粒的进一步研究提供参考。

Protein nanoparticles, as antigen display carriers, can effectively help to improve the stability and immunogenicity of antigens due to their similar size to natural pathogens. Clinical trials have shown that protein nanoparticles can be used in the development of novel vaccines. This paper reviews the immunological properties of protein nanoparticle vaccine and the application in vaccine research and development, aiming to provide reference for further research of protein nanoparticle.