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鸡卵黄抗体IgY在临床医学中的应用

  • 杜洪桥 严家新
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  • 430060,中国医药集团武汉生物制品研究所基因工程室

网络出版日期: 2025-08-16

Applications of chicken yolk IgY in clinical medicine

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  • Laboratory of Genetic Engineering, Wuhan Institute of Biological Products, Sinopharm, Wuhan 430060,China

Online published: 2025-08-16

摘要

卵黄抗体又称卵黄免疫球蛋白(IgY),是一种7s免疫球蛋白。与哺乳动物IgG略有不同,在母鸡血清中选择性地转移到卵黄,是卵黄中唯一的免疫球蛋白。由于IgY具有化学性质稳定、产量高、成本低以及动物种系发生学距离的优势,使得IgY在制备多克隆抗体、免疫检测诊断、人类和动物疾病的预防治疗方面均得到了广泛的应用。  

本文引用格式

杜洪桥 严家新 . 鸡卵黄抗体IgY在临床医学中的应用[J]. 国际生物制品学杂志, 2011 , 34(6) : 322 -326 . DOI: 10.3760/cma.j,issn. 1673-4211.2011.06.011

Abstract

 Yolk antibody known as immunoglobulin yolk (IgY), is a 7s immunoglobulin. It is selectively transferred from hen serum to the yolk and is the only antibody in yolk which is slightly different from mammalian IgG. Since IgY possesses advantages of chemical stability, high productivity, low cost, and animal phylogenetic distance, it has a wide range of applications in polyclonal antibodies preparation, immunoassay, human and animal disease prevention and treatment.
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