综述

脐带血干细胞移植治疗肝脏疾病的研究进展

  • 王博 王毅军 朱争艳
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  • 300170   天津医科大学三中心临床学院(王博);天津市第三中心医院,天津市人工细胞重点实验室,天津市肝胆疾病研究所,天津市再生医学与疾病生物治疗工程研究中心(王毅军、朱争艳)

网络出版日期: 2025-08-16

Research progress in umbilical cord blood stem cell transplantation for treatment of liver diseases

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  • *The Third Central Hospital , Tianjin  Medical University;Tianjin Key Laboratory of Artificial Cell,Tianjin 300170,China

Online published: 2025-08-16

摘要

脐带血干细胞(umbilical cord blood stem cells,UCBSC)移植是最有前景的干细胞移植之一。目前,UCBSC在肝脏疾病方面所作的基础实验研究显示,UCBSC 可在体内外大量扩增并诱导分化为有肝功能的肝细胞样细胞。UCBSC 移植治疗与肝脏疾病的关系,由于相关的临床应用研究较少,目前还没有确切定论。此文就 UCBSC 移植治疗肝脏疾病作一综述。

本文引用格式

王博 王毅军 朱争艳 . 脐带血干细胞移植治疗肝脏疾病的研究进展[J]. 国际生物制品学杂志, 2011 , 34(6) : 313 -317,303 . DOI: 10.3760/cma.j.issn.1673-4211.2011.06.009

Abstract

Umbilical cord blood stem cells (UCBSC) transplantation is one of the most promising stem cell transplantation. Currently, basic experimental studies of UCBSC in liver
diseases have shown that UCBSC can be greatly amplified and induced to differentiate into functional hepatocyte-like cells in vivo and in vitro. The relationship between treatment of UCBSC transplantation and liver diseases has not yet been determined, because there are few relevant studies on clinical application. In this paper, UCBSC transplantation for treatment of liver diseases is reviewed.
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